In which organelles would an enzyme that adds a palmityl group to proteins likely be processed?

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The enzymes that add a palmityl group to proteins, which is a type of lipid modification known as palmitoylation, are typically processed in the Golgi apparatus and endoplasmic reticulum.

The endoplasmic reticulum (ER) is the site where proteins are initially synthesized and undergo folding and modifications. It contains enzymes that can facilitate the addition of lipid groups to proteins. Once these modifications are made, the proteins are transported to the Golgi apparatus, where further processing, sorting, and packaging occur. The Golgi is crucial for post-translational modifications and is responsible for adding final touches, including lipid modifications like palmitoylation.

This sequence of processing in the ER and Golgi apparatus is vital for ensuring that proteins are correctly modified, folded, and sent to their proper destinations within or outside the cell.

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