What is the purpose of cell adhesion molecules during diapedesis?

The purpose of cell adhesion molecules during diapedesis is to help white blood cells adhere to the walls of blood vessels. Diapedesis is the process by which white blood cells exit the bloodstream and move into surrounding tissues, especially during an immune response. Cell adhesion molecules, such as selectins and integrins, play a crucial role in this process by facilitating the binding of white blood cells to the endothelial cells of blood vessels. This adhesion is essential for the migration of these immune cells towards areas where they are needed, such as sites of infection or inflammation. By assisting in this process, cell adhesion molecules ensure that white blood cells can respond effectively to immune challenges.