What is the main distinguishing feature of ribozymes compared to typical enzymes?

The main distinguishing feature of ribozymes is that they contain catalytic RNA. Unlike typical enzymes, which are primarily composed of proteins and catalyze biochemical reactions through their amino acid sequences, ribozymes are RNA molecules that can fold into specific three-dimensional shapes, enabling them to catalyze chemical reactions. This capability highlights the versatility of RNA, which can serve not only as genetic material but also as a functional catalyst.

The presence of catalytic RNA signifies a critical evolutionary transition, illustrating that RNA was likely an essential component in early life forms, possibly predating protein-based enzymes. By demonstrating that RNA can perform catalytic functions, ribozymes challenge the traditional view that only proteins can serve as biological catalysts.

Other options do not align with the defining characteristics of ribozymes, emphasizing their nucleic acid basis rather than an amino acid structure or a function unrelated to catalysis or biological processes.